Anti-Mouse F4/80 Antigen PE 抗小鼠F4/80抗原PE抗体

• 产品型号：  eBiosience12-4801-82
• 简单描述
• Host
  Rat
  Isotype
  IgG2a, kappa
  Reactivity
  Mouse
  Conjugate
  PE
  Laser
  Blue Laser, Green Laser, Yellow-Green Laser
  Emit
  575 nm
  Excite
  488 – 561 nm
  Reported Applications
  Flow Cytometric Analysis

Also known as: Pan Macrophage Marker

Clone: BM8

Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximay 125 kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo

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